Sigma Receptor
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Sigma Receptor Related Products (108)
Related Products (108)
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5-Phenyllevulinic acid
0 ImagesCat. No.: HY-W714837CAS No.: 3183-15-1Synonyms: 4-Oxo-5-phenylpentanoic acid; 5-Phenyl-4-oxopentanoic acid5-Phenyllevulinic acid (4-Oxo-5-phenylpentanoic acid) is an endogenous fungal metabolite with inhibitory activity against the bacterium B. megaterium, the plant pathogenic fungus S. tritici, and the alga C. fusca. 5-Phenyllevulinic acid is also an intermediate in the synthesis of σ receptor ligands. 5-Phenyllevulinic acid holds potential for research in the field of anti-infection studies .
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Oxeladin citrate (Standard)
0 ImagesCat. No.: HY-B1216RCAS No.: 52432-72-1Oxeladin (citrate) (Standard) is the analytical standard of Oxeladin (citrate). This product is intended for research and analytical applications. Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research.
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SV119 hydrochloride
0 ImagesCat. No.: HY-177345ACAS No.: 913816-12-3SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM. SV119 hydrochloride enhances the efficient transport of drugs across the plasma membrane of cancer cells. The conjugation of dm-Erastin with SV119 hydrochloride successfully overcomes the internalization barrier observed in pancreatic cancer, while preserving the inherent anti-tumor activity of Erastin (HY-15763). Additionally, SV119 hydrochloride demonstrates cytotoxic effects on triple-negative breast cancer (TNBC) cells and induces apoptosis.
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Sigma-2 Radioligand 2
0 ImagesCat. No.: HY-169185CAS No.: 2860554-31-8Sigma-2 Radioligand 2 (compund 4) exhibits low nanomolar affinity (Ki(σ2)=2.30 nM) and high subtype selectivity (Ki(σ1)/Ki(σ2) > 1500) for the σ2 receptor.
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Cutamesine dihydrochloride (Standard)
0 ImagesSynonyms: SA4503 dihydrochloride (Standard); AGY94806 dihydrochloride (Standard)Cutamesine dihydrochloride (Standard) is the analytical standard of Cutamesine dihydrochloride. This product is intended for research and analytical applications. Cutamesine dihydrochloride (SA4503 dihydrochloride; AGY94806 dihydrochloride) is a potent Sigma 1 receptor agonist with an IC50 of 17.4 nM in guinea pig brain membranes.
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Sigma ligand-1 (Standard)
0 ImagesCat. No.: HY-101626RCAS No.: 139652-01-0Sigma ligand-1 (Standard) is the analytical standard of Sigma ligand-1 (HY-101626). This product is intended for research and analytical applications. Sigma ligand-1 is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma ligand-1 has a Ki of 4000 nM at the dopamine D2 receptor.
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Sigma ligand-1 hydrochloride (Standard)
0 ImagesCat. No.: HY-101626ARCAS No.: 139652-86-1Sigma ligand-1 (hydrochloride) (Standard) is the analytical standard of Sigma ligand-1 (hydrochloride) (HY-101626A). This product is intended for research and analytical applications. Sigma ligand-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma ligand-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor.
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Opipramol (Standard)
0 ImagesCat. No.: HY-118901RCAS No.: 315-72-0Synonyms: Ensidon (Standard); G-33040 (Standard)Opipramol (Standard) is the analytical standard of Opipramol. This product is intended for research and analytical applications. Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD).
